Lorenzo's Oil Vindicated
Press Release

Dunn Loring, Va., Sept. 26, 2002-On September 28th, Dr. Hugo Moser of the Kennedy Krieger Institute in Baltimore, Maryland, will present the results of a long-term study on the preventive efficacy of Lorenzo's Oil. This is an international study conducted in collaboration with 12 other laboratories. The presentation will be made within the framework of the International Symposium on Peroxisomal Disorders and Regulations of Genes at Ghent University sponsored by the Belgian Society for Cell and Developmental Biology.

The study involved 104 asymptomatic ALD (adrenoleukodystrophy) boys under six years of age, 69 in the US, 36 in Europe. While some boys followed scrupulously the Lorenzo's Oil regime, others did not. In the first group of boys their level of Very Long Chain Fatty Acids (the metabolite accumulating in ALD) fell to within 2 standard deviations from normal. In the second group the VLCFA remained abnormally high.

A comparison between the 2 groups showed that for the boys who followed the Lorenzo's Oil regime, the hazard (or risk) of developing the childhood form of the disease was 23% of that of the noncompliant boys. This is not to say that the boys who overcame the critical age of childhood ALD (generally 10 years of age) will not develop the adult form (AMN), which usually manifests itself toward the end of the third decade of life.

These results of the study will come as a shock to the medical community. While admitting that Lorenzo's Oil has the property of normalizing the level of the VLCFA, most doctors have denied for many years its therapeutic value.
One of the merits of the study was to demonstrate for the first time that the VLCFA are indeed involved in the pathogenesis of ALD.

The inventors of Lorenzo's Oil are the late Michaela Odone and her husband Augusto Odone. Mr. Odone has recently obtained a patent on Lorenzo's Oil (Patent No. 5,331,009). As the second chapter of his quest to find a therapy that could restore the myelin sheath which gets destroyed in ALD, Mr. Odone is currently forging ahead with The Myelin Project. If this is successful it will help not only the children of the leukodystrophies, but also the adults who suffer from Multiple Sclerosis in whom the myelin sheath is similarly destroyed.

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